Why Do We Fall Ill ?

13.1 Health and its Failure

13.1.1 The Significance of ‘Health’

‘Health’ is therefore a state of being well enough to function well physically, mentally and socially.

While being interested in following the teaching in the classroom so that we can understand the world is called a ‘healthy attitude’; while not being interested is called the opposite.

13.1.2 Personal and Community Issues Both Matter For Health

If health means a state of physical, mental and social well-being, it cannot be something that each one of us can achieve entirely on our own. The health of all organisms will depend on their surroundings or their environment.

Human beings live in societies. Our social environment, therefore, is an important factor in our individual health. The public cleanliness is important for individual health and Social equality and harmony are therefore necessary for individual health.

13.1.3 Distinctions Between ‘Healthy’ and ‘Disease-Free’

Disease, in other words, literally means being uncomfortable. However, the word is used in a more limited meaning. We talk of disease when we can find a specific and particular cause for discomfort. It is possible to be in poor health without actually suffering from a particular disease. Simply not being diseased is not the same as being healthy. When we think about disease, we think about individual sufferers.

Good health for a musician may mean having enough breathing capacity in his/her lungs to control the notes from his/her flute. To have the opportunity to realise the unique potential in all of us is also necessary for real health.

13.2 Disease and Its Causes

13.2.1 What Does Disease Look Like?

When there is a disease, either the functioning of one or more systems of the body will change for the worse. These changes give rise to symptoms and signs of disease.

Symptoms of disease are the things we feel as being ‘wrong’. So we have a headache, we have cough, we have loose motions, we have a wound with pus; these are all symptoms.

These indicate that there may be a disease, but they don’t indicate what the disease is. For example, a headache may mean just examination stress or, very rarely, it may mean meningitis, or any one of a dozen different diseases.

Signs of disease are what physicians will look for on the basis of the symptoms. Signs will give a little more definite indication of the presence of a particular disease. Physicians will also get laboratory tests done to pinpoint the disease further.

13.2.2 Acute and Chronic Diseases

The manifestations of disease will be different depending on a number of factors. Some diseases last for only very short periods of time, and these are called acute diseases.

13.2.3 Chronic Diseases and Poor Ealth

Acute and chronic diseases have different effects on our health. Any disease that causes poor functioning of some part of the body will affect our health. This is because all functions of the body are necessary for being healthy.

In general poor health if we have a chronic disease. Chronic diseases therefore, have very drastic long-term effects on people's health as compared to acute diseases.

13.2.4 Causes of Diseases

When we think about causes of diseases, we must remember that there are many levels of such causes. The infection can be come through unclean drinking water. Without the pathogen, the genetic difference or the poor nourishment alone would not lead to loose motions. But they do become contributory causes of the disease.

It will now be obvious that all diseases will have immediate causes and contributory causes. Also, most diseases will have many causes, rather than one single cause.

13.2.5 Infectious and Non-Infectious Causes

It is important to keep public health and community health factors in mind when we think about causes of diseases. One group of causes is the infectious agents, mostly microbes or micro-organisms. Diseases where microbes are the immediate causes are called infectious diseases. This is because the microbes can spread in the community, and the diseases they cause will spread with them.

There are also diseases that are not caused by infectious agents. Their causes vary, but they are not external causes like microbes that can spread in the community. Instead, these are mostly internal, non-infectious causes.

The ways in which diseases spread, and the ways in which they can be treated and prevented at the community level would be different for different diseases. This would depend a lot on whether the immediate causes are infectious or non-infectious.

13.3 Infectious Diseases

13.3.1 Infectious Agents

Organisms that can cause disease are found in a wide range of such categories of classification. Some of them are viruses, some are bacteria, some are fungi, some are single-celled animals or protozoans.

Some diseases are also caused by multicellular organisms, such as worms of different kinds.

Common examples of diseases caused by viruses are the common cold, influenza, dengue fever and AIDS.

Diseases like typhoid fever, cholera, tuberculosis and anthrax are caused by bacteria.

Many common skin infections are caused by different kinds of fungi.

Protozoan microbes cause many familiar diseases, such as malaria and kalaazar.

All of us have also come across intestinal worm infections, as well as diseases like elephantiasis caused by diffferent species of worms.

Commonly the biochemical block pathways important for bacteria. Many bacteria, for example, make a cell-wall to protect themselves. The antibiotic penicillin blocks the bacterial processes that build the cellwall.

Human cells don’t make a cell-wall anyway, so penicillin cannot have such an effect on us. Penicillin will have this effect on any bacteria that use such processes for making cell-walls. Similarly, many antibiotics work against many species of bacteria rather than simply working against one.

But viruses do not use these pathways at all, and that is the reason why antibiotics do not work against viral infections. If we have a common cold, taking antibiotics does not reduce the severity or the duration of the disease.

13.3.2 Means of Spread

Many microbial agents can commonly move from an affected person to someone else in a variety of ways. In other words, they can be ‘communicated’, and so are also called communicable diseases.

Such disease-causing microbes can spread through the air. This occurs through the little droplets thrown out by an infected person who sneezes or coughs. Someone standing close by can breathe in these droplets, and the microbes get a chance to start a new infection. the more crowded our living conditions are, the more likely it is that such airborne diseases will spread.

Diseases can also be spread through water. This occurs if the excreta from someone suffering from an infectious gut disease, such as cholera, get mixed with the drinking water used by people living nearby.

The sexual act is one of the closest physical contact two people can have with each other.

Not surprisingly, there are microbial infections such as syphilis or AIDS that are transmitted by sexual contact from one partner to the other. However, such sexually transmitted diseases are not spread by casual physical contact.

The commonest vectors we all know are mosquitoes. In many species of mosquitoes, the females need highly nutritious food in the form of blood in order to be able to lay mature eggs. Mosquitoes feed on many warm-blooded animals, including us. In this way, they can transfer diseases from person to person.

13.3.3 Organ-Specific and Tissuespecific Manifestations

The disease-causing microbes enter the body through these different means. Different species of microbes seem to have evolved to home in on different parts of the body.

The virus causing Japanese encephalitis, or brain fever, will similarly enter through a mosquito bite. But it goes on to infect the brain. The signs and symptoms of a disease will thus depend on the tissue or organ which the microbe targets. If the lungs are the targets, then symptoms will be cough and breathlessness. If the liver is targeted, there will be jaundice. If the brain is the target, we will observe headaches, vomiting, fits or unconsciousness.

An active immune system recruits many cells to the affected tissue to kill off the disease-causing microbes. This recruitment process is called inflammation.

13.3.4 Principles of Treatment

Provide treatment that will reduce the symptoms. The symptoms are usually because of inflammation. For example, we can take medicines that bring down fever, reduce pain or loose motions.

The antibiotics that we are all familiar with. Similarly, there are drugs that kill protozoa such as the malarial parasite.

There are relatively few virus-specific targets to aim at. Despite this limitation, there are now effective anti-viral drugs, for example, the drugs that keep HIV infection under control.

13.3.5 Principles of Prevention

The first is that once someone has a disease, their body functions are damaged and may never recover completely. The second is that treatment will take time, which means that someone suffering from a disease is likely to be bedridden for some time even if we can give proper treatment. The third is that the person suffering from an infectious disease can serve as the source from where the infection may spread to other people.

The immune system of our body is normally fighting off microbes. We have cells that specialise in killing infecting microbes. These cells go into action each time infecting microbes enter the body. If they are successful, we do not actually come down with any disease. The immune cells manage to kill off the infection long before it assumes major proportions.

The functioning of the immune system, like any other system in our body, will not be good if proper and sufficient nourishment and food is not available. Therefore, the second basic principle of prevention of infectious disease is the availability of proper and sufficient food for everyone.